Cell Design Tools and Resources
At the Cell Design Institute we produce open source tools, systems and constructs to broadly enable cell engineering. Technologies listed below are directly available for non-profit/academic researchers on open source platforms like Addgene and GitHub. For profit entities interested in technology licensing can contact Todd Pazdera (UCSF Innovation Ventures)
Molecular Components and Circuits
SynNotch Receptor: Cell-Cell Sense-Response Platform
https://www.addgene.org/79125/
https://www.addgene.org/79127/
https://www.addgene.org/79130/
https://www.addgene.org/79129/
https://www.addgene.org/79126/
https://www.addgene.org/79128/
https://www.addgene.org/79119/
https://www.addgene.org/79123/
https://www.addgene.org/79121/
https://www.addgene.org/79124/
Mammalian Toolkit: modular engineering of mammalian circuits
LOCKR degron system
https://www.addgene.org/50839/
https://www.addgene.org/50839/
https://www.addgene.org/50839/
https://www.addgene.org/50839/
https://www.addgene.org/50839/
https://www.addgene.org/50839/
Cellular Optogenetic Systems
Phy-PIF systemshttps://www.addgene.org/50839/
https://www.addgene.org/50851/
https://www.addgene.org/50848/
Optoplatehttps://www.bugajlab.com/optoplate-96
https://www.nature.com/articles/s41596-019-0178-y
Clasphttps://www.addgene.org/133086/